Signaling pathways are protein networks involved in multiple cell-development processes like apoptosis, angiogenesis, proliferation, differentiation and so on. Creative BioMart specializes in cell pathways profiling. Our specific antibodies enable to analyze the dysregulation and phosphorylation status of key cell signaling pathways studied in drug discovery and therapeutic development.

Main applications:

• Study of disease mechanisms in biological samples or fixed tissues
• Identification of pathways involved in drug resistance
• Early evaluation of drug efficacy (dose response, time course) and mechanism of action in cell based assays
• Evaluation of combination therapies
• Fingerprint comparison of biologics and biosimilar activity
• Assessment of in vitro or animals models